INSIGHT
Harry Sarimveis@hsarimv@mail.ntua.gr
INSIGHT is a project funded by Horizon Europe (GA101137742). The Project aims to:
- Develop an integrated framework for mechanistic impact assessment based on the novel concept of IOP;
- Provide curated and user-friendly FAIR data and computational models and workflows that support the development of the next generation SSbD chemicals and materials;
- Provide open, accessible and interactive guidelines, enabling end users and stakeholders to access and operate the framework.
For more information visit https://insight-project.org/
| Title | Model Description |
| QSAR toolbox Calculator integration | This service provides access to the calculators included in the QSAR toolbox |
| QSAR Toolbox Model Integration | This service provides access to the QSAR models included in the QSAR toolbox |
| QSAR Toolbox Profiler integration | This service provides access to the profilers included in the QSAR toolbox |
| Extended PFOA male rat PBK | This is a PBK model that predicts the biodistribution of PFOA in rats after oral exposure or IV injection |
| PFOA rat_Worley | This is a PBK model that predicts the biodistribution of PFOA in rats after oral exposure or IV injection |
| PFASs Human PBPK | This is a PBK model that predicts the biodistribution of PFBS, PFHxS, PFOS, PFDS, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnDA or PFTeDA in humans after oral exposure |
| PFAAs Protein-Binding Fish PBK | This is a PBK model that predicts the biodistribution of PFOS, PFOA, PFDA, PFUnA, PFDoA or PFHxS in fish after waterborne exposure |
| PFOS/PFOA Human PBPK (Oral exposure) | This is a PBPK model that predicts the accumulation of PFOS or PFOA in humans after oral exposure |
| PFOS Rainbow trout PBTK | This is a PBK model that predicts the biodistribution of PFOS in R. trout after oral or waterborne exposure |
| PFOS/PFOA Human PBK | This is a PBK model that predicts the biodistribution of PFOS or PFOA in humans after oral exposure or IV injection |
| PFOA rat PBK | This is a PBK model that predicts the biodistribution of PFOA in rats after oral exposure or IV injection |
| PFOS rat PBK | This is a PBK model that predicts the biodistribution of PFOS in rats after oral exposure or IV injection |
| PFHxS rat PBK | This is a PBK model that predicts the biodistribution of PFHxS in rats after oral exposure or IV injection |
| PFNA rat PBK | This is a PBK model that predicts the biodistribution of PFNA in rats after oral exposure or IV injection |
| PFDA rat PBK | This is a PBK model that predicts the biodistribution of PFDA in rats after oral exposure or IV injection |
| PFAS PBK Zebrafish | This is a PBK model that predicts the biodistribution of PFOA, PFHpA, PFNA, PFHxS, or PFBS in zebrafish through waterborne exposure |