PFNA rat PBK

7 months ago

R_PBPK

Independent Features

Name	Units	Description	Type
admin.type		Type of administration	CATEGORICAL
admin.dose	mg	Administered dose	FLOAT_ARRAY
admin.time	hours	Time corresponding to dose administration	FLOAT_ARRAY
BW	kg	Body weight	FLOAT_ARRAY
BW.times	hours	Time points corresponding to body weight	FLOAT_ARRAY
F_unabs	-	Fraction of unabsorbed oral dose	FLOAT
sex		Sex of rat	CATEGORICAL
sim.start	hours	First point of the simulation time vector	FLOAT
sim.end	hours	Last point of the simulation time vector	FLOAT
sim.step	hours	Time increment of the simulation time vector	FLOAT

Name	Units	Description	Type
A_li	mg	Amount of PFNA in liver	FLOAT
A_gi	mg	Amount of PFNA in GI tract	FLOAT
A_ki	mg	Amount of PFNA in kidneys	FLOAT
A_fil	mg	Amount of PFNA in filtrate	FLOAT
A_rb	mg	Amount of PFNA in rest-of-the-body	FLOAT
A_bl	mg	Amount of PFNA in blood	FLOAT
A_lu	mg	Amount of PFNA in lungs	FLOAT
A_ht	mg	Amount of PFNA in heart	FLOAT
A_fecal	mg	Amount of PFNA in feces	FLOAT
A_urine	mg	Amount of PFNA in urine	FLOAT
A_fst	mg	Amount of PFNA in fecal storage	FLOAT
A_ust	mg	Amount of PFNA in urine storage	FLOAT
A_glumen	mg	Amount of PFNA in git lumen	FLOAT
C_li	mg/L	Concentration of PFNA in liver	FLOAT
C_gi	mg/L	Concentration of PFNA in GI tract	FLOAT
C_ki	mg/L	Concentration of PFNA in kidneys	FLOAT
C_fil	mg/L	Concentration of PFNA in filtrate	FLOAT
C_rb	mg/L	Concentration of PFNA in rest-of-the-body	FLOAT
C_bl	mg/L	Concentration of PFNA in blood	FLOAT
C_lu	mg/L	Concentration of PFNA in lungs	FLOAT
C_ht	mg/L	Concentration of PFNA in heart	FLOAT
BW_out	kg	Body weight measurements	FLOAT
time	hours	Simulation time vector	FLOAT