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TiO2 iv rat PBK model
Independent Features
| Name | Units | Range | Description | Type | Actions |
|---|---|---|---|---|---|
dose | μg | TiO2 nanoparticles IV dose(s) administered | FLOAT | ||
mass | g | Mass of the rat | FLOAT | ||
administration_time | hours | Time points during which TiO2 IV administration took place | FLOAT | ||
sim.start | hours | First point of the simulation time vector | FLOAT | ||
sim.end | hours | Last point of the simulation time vector | FLOAT | ||
sim.step | hours | Time increment of the simulation time vector | FLOAT |
Dependent Features
| Name | Units | Description | Type | Actions |
|---|---|---|---|---|
| Blood | ug/g | Concentration of NPs in blood | FLOAT | |
| Heart | ug/g | Concentration of NPs in heart | FLOAT | |
| Lungs | ug/g | Concentration of NPs in lungs | FLOAT | |
| Liver | ug/g | Concentration of NPs in liver | FLOAT | |
| Spleen | ug/g | Concentration of NPs in spleen | FLOAT | |
| Kidneys | ug/g | Concentration of NPs in kidneys | FLOAT | |
| Git | ug/g | Concentration of NPs in gastrointestinal tract | FLOAT | |
| Bone | ug/g | Concentration of NPs in bones | FLOAT | |
| RoB | ug/g | Concentration of NPs in rest-of-the body | FLOAT | |
| Feces | ug | Cumulative mass of NPs in feces | FLOAT | |
| Urine | ug | Cumulative NP mass in urine | FLOAT | |
| time | hours | Simulation time vector | FLOAT |