PFAAs Protein-Binding Fish PBK

PFAAs Protein-Binding Fish PBK | Jaqpot

over 2 years ago

R_PBPK

Independent Features

Name	Units	Description	Type
BW	kg	Fish bodyweight	FLOAT
substance		Exposure substance	CATEGORICAL
admin.dose	mol/m^3	PFAS concentration in water	FLOAT_ARRAY
admin.time	s	Time points of substance intake.	FLOAT_ARRAY
sim.start	s	Initial time point of simulation.	FLOAT
sim.end	s	Final time point of simulation.	FLOAT
sim.step	s	The integration step of simulation.	FLOAT

Name	Units	Description	Type
C_W_free	mol/m^3	Concentration of free PFAS in water	FLOAT
M_B_free	mol	Mass of free PFAS in blood	FLOAT
M_B_bound	mol	Mass of bound PFAS in blood	FLOAT
M_AF_free	mol	Mass of free PFAS in adipose fluid	FLOAT
M_AF_bound	mol	Mass of bound PFAS in adipose fluid	FLOAT
M_AT_free	mol	Mass of free PFAS in adipose tissue	FLOAT
M_MF_free	mol	Mass of free PFAS in muscle fluid	FLOAT
M_MF_bound	mol	Mass of bound PFAS in muscle fluid	FLOAT
M_MT_free	mol	Mass of free PFAS in muscle tissue	FLOAT
M_LF_free	mol	Mass of free PFAS in liver fluid	FLOAT
M_LF_bound	mol	Mass of bound PFAS in liver fluid	FLOAT
M_LT_free	mol	Mass of free PFAS in liver tissue	FLOAT
M_LT_bound	mol	Mass of bound PFAS in liver tissue	FLOAT
M_KF_free	mol	Mass of free PFAS in kidney fluid	FLOAT
M_KF_bound	mol	Mass of bound PFAS in kidney fluid	FLOAT
M_KT_free	mol	Mass of free PFAS in kidney tissue	FLOAT
M_Ur_free	mol	Mass of free PFAS in urine	FLOAT
C_B_ALB	mol/m^3	Concentration of albumin in blood	FLOAT
C_AF_ALB	mol/m^3	Concentration of albumin in adipose fluid	FLOAT
C_MF_ALB	mol/m^3	Concentration of albumin in muscle fluid	FLOAT
C_LF_ALB	mol/m^3	Concentration of albumin in liver fluid	FLOAT
C_LT_FAPB	mol/m^3	Concentration of fatty acid binding protein in liver tissue	FLOAT
C_KF_ALB	mol/m^3	Concentration of albumin in kidney fluid	FLOAT
time	h	Simulation time vector	FLOAT