The PINK EU project aims at providing integrated computational approaches for the introduction of safe-and-sustainable-by-design chemicals and materials into the market. PINK will develop a Tiered Approach, where each development cycle will start with mining and creating data on the functionality, safety, and sustainability, as well as cost/economic feasibility, which will be provided simultaneously as input for the decision support workflow. The PINK Tiered Approach will categorise all computational methods into three tiers that parallel the material development TRLs, with respect to their data needs, throughput, and confidence levels. At earlier development stages (ideation/design phase of material development), where less data is available, high-throughput computational approaches of low tiers will be applied to avoid limiting the exploration and missing promising design routes due to time constraints (human and computer) and costs.
For more information visit https://pink-project.eu/
Title | Model Description | |
QSAR toolbox Calculator integration | This service provides access to the calculators included in the QSAR toolbox | |
QSAR Toolbox Model Integration | This service provides access to the QSAR models included in the QSAR toolbox | |
QSAR Toolbox Profiler integration | This service provides access to the profilers included in the QSAR toolbox | |
DILI Prediction Model | This model predicts if a substance induces liver injury | |
IndusChemFate PBTK | IndusChemFate is a PBTK model designed to estimate blood and urine concentrations of multiple chemicals and their metabolites given specific exposure scenarios. | |
IndusChemFate Lite PBTK | A lite version of IndusChemFate PBTK model, limiting metabolism to liver-only and single metabolites, reducing complexity and parameter requirements compared to the original model |