Human pregnancy-PBPK model for a mix of pyrethroids

Human pregnancy-PBPK model for a mix of pyrethroids | Jaqpot

6 months ago

R_PBPK

Independent Features

Name	Units	Description	Type
Bodyweight (kg)	kg		FLOAT
Age at the end of the pregnancy (years)	year		FLOAT
Age at the start of the pregnancy (years)	year		FLOAT
Pregnancy duration (weeks)	weeks		FLOAT
Permethrin ingestion rate (µg/kg bw/day)	µg/kg bw/d		FLOAT_ARRAY
Time of permethrin ingestion rate (day)	day		FLOAT_ARRAY
Cypermethrin ingestion rate (µg/kg bw/day)	µg/kg bw/d		FLOAT_ARRAY
Time of cypermethrin ingestion rate (day)	day		FLOAT_ARRAY
Deltamethrin ingestion rate (µg/kg bw/day)	µg/kg bw/d		FLOAT_ARRAY
Time of deltamethrin ingestion rate (day)	day		FLOAT_ARRAY
sim.start	day	This feature must be in accordance with the age of the exposure period	FLOAT
sim.end	day	This feature must be in accordance with the age of the exposure period	FLOAT
sim.step	day		FLOAT

Name	Units	Type
CcisPM_ven	µg/L	FLOAT
CcisPM_brain	µg/L	FLOAT
CtransPM_ven	µg/L	FLOAT
CtransPM_brain	µg/L	FLOAT
CcisCYP_ven	µg/L	FLOAT
CcisCYP_brain	µg/L	FLOAT
CtransCYP_ven	µg/L	FLOAT
CtransCYP_brain	µg/L	FLOAT
CDLT_ven	µg/L	FLOAT
CDLT_brain	µg/L	FLOAT
Curi_cisDCCA	µg/L	FLOAT
Curi_transDCCA	µg/L	FLOAT
Curi_DBCA	µg/L	FLOAT
Curi_PBA	µg/L	FLOAT
Curi_DCCA	µg/L	FLOAT
CcisPM_foetus_3	µg/L	FLOAT
CcisPM_foetus_brain	µg/L	FLOAT
CcisPM_foetus_ven	µg/L	FLOAT
CtransPM_foetus_3	µg/L	FLOAT
CtransPM_foetus_brain	µg/L	FLOAT
CtransPM_foetus_ven	µg/L	FLOAT
CcisCYP_foetus_3	µg/L	FLOAT
CcisCYP_foetus_brain	µg/L	FLOAT
CcisCYP_foetus_ven	µg/L	FLOAT
CtransCYP_foetus_3	µg/L	FLOAT
CtransCYP_foetus_brain	µg/L	FLOAT
CtransCYP_foetus_ven	µg/L	FLOAT
CDLT_foetus_3	µg/L	FLOAT
CDLT_foetus_brain	µg/L	FLOAT
CDLT_foetus_ven	µg/L	FLOAT
time	day	FLOAT