PFHxS rat PBK | Jaqpot

PFHxS rat PBK

about 1 year ago

R_PBPK

Independent Features

Name	Units	Description	Type
admin.type		Type of administration	CATEGORICAL
admin.dose	mg	Administered dose	FLOAT_ARRAY
admin.time	hours	Time corresponding to dose administration	FLOAT_ARRAY
BW	kg	Body weight	FLOAT_ARRAY
BW.times	hours	Time points corresponding to body weight	FLOAT_ARRAY
F_unabs	-	Fraction of unabsorbed oral dose	FLOAT
sex		Sex of rat	CATEGORICAL
sim.start	hours	First point of the simulation time vector	FLOAT
sim.end	hours	Last point of the simulation time vector	FLOAT
sim.step	hours	Time increment of the simulation time vector	FLOAT

Name	Units	Description	Type
A_li	mg	Amount of PFHxS in liver	FLOAT
A_gi	mg	Amount of PFHxS in liver	FLOAT
A_ki	mg	Amount of PFHxS in kidneys	FLOAT
A_fil	mg	Amount of PFHxS in filtrate	FLOAT
A_rb	mg	Amount of PFHxS in rest-of-the-body	FLOAT
A_bl	mg	Amount of PFHxS in blood	FLOAT
A_lu	mg	Amount of PFHxS in lungs	FLOAT
A_ht	mg	Amount of PFHxS in heart	FLOAT
A_br	mg	Amount of PFHxS in brain	FLOAT
A_fecal	mg	Amount of PFHxS in feces	FLOAT
A_urine	mg	Amount of PFHxS in urine	FLOAT
A_fst	mg	Amount of PFHxS in fecal storage	FLOAT
A_ust	mg	Amount of PFHxS in urine storage	FLOAT
A_glumen	mg	Amount of PFHxS in gut lumen	FLOAT
C_li	mg/L	Concentration of PFHxS in liver	FLOAT
C_gi	mg/L	Concentration of PFHxS in GI tract	FLOAT
C_ki	mg/L	Concentration of PFHxS in kidneys	FLOAT
C_fil	mg/L	Concentration of PFHxS in filtrate	FLOAT
C_rb	mg/L	Concentration of PFHxS in rest-of-the-body	FLOAT
C_bl	mg/L	Concentration of PFHxS in blood	FLOAT
C_lu	mg/L	Concentration of PFHxS in lungs	FLOAT
C_ht	mg/L	Concentration of PFHxS in heart	FLOAT
C_br	mg/L	Concentration of PFHxS in brain	FLOAT
BW_out	kg	Measurements of body weight	FLOAT
time	hours	Simulation time vector	FLOAT